Pharmacology · single question

For a patient on methotrexate and Humira, which lab value is most important to monitor for drug safety?

  1. Creatinine (renal function)
  2. Sodium
  3. Calcium
  4. Uric acid
Show answer and explanation

Correct answer: A. Creatinine (renal function)

  • A. Correct. Methotrexate is renally excreted; impaired renal function raises toxicity risk, so creatinine (with LFTs and CBC) is monitored.
  • B. Sodium is not a primary methotrexate-monitoring parameter.
  • C. Calcium is unrelated to methotrexate safety monitoring.
  • D. Uric acid is not the key monitored value for these drugs.

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