Pharmacology · single question
What is the mechanism of action of statins (on the patient's medication list)?
Show answer and explanation
Correct answer: A. Inhibit HMG-CoA reductase
- A. Correct. Statins competitively inhibit HMG-CoA reductase, the rate-limiting enzyme in hepatic cholesterol synthesis, lowering LDL.
- B. Cholesterol-absorption inhibition describes ezetimibe.
- C. Bile-acid binding describes resins like cholestyramine.
- D. Activating lipoprotein lipase is not the statin mechanism.