Micro & Immunology · single question

Following a facial (CN VII) herpes zoster infection, where does the virus remain latent?

  1. Submandibular ganglion
  2. Otic ganglion
  3. Geniculate ganglion
  4. Trigeminal (Gasserian) ganglion
Show answer and explanation

Correct answer: C. Geniculate ganglion

  • A. Incorrect. The submandibular ganglion is a parasympathetic relay for CN VII secretomotor fibres, not a sensory latency site.
  • B. Incorrect. The otic ganglion is a parasympathetic relay for CN IX to the parotid, not a viral latency site.
  • C. Correct. Varicella zoster involving the facial nerve (Ramsay Hunt syndrome) reactivates from the geniculate ganglion — the sensory ganglion of CN VII located at the genu of the facial canal.
  • D. Incorrect. The trigeminal ganglion houses latent HSV-1 and is the source of zoster affecting the V1/V2/V3 dermatomes.

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