Micro & Immunology · single question
Anaphylaxis is classified as which type of hypersensitivity reaction?
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Correct answer: D. Type I (IgE-mediated)
Anaphylaxis = TYPE I (immediate) IgE-mediated hypersensitivity. First exposure → IgE binds mast cells. Second exposure → cross-linking IgE → massive degranulation → histamine, leukotrienes → vasodilation, bronchoconstriction, hypotension. Treatment: epinephrine 1:1,000.
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