During which period does tetracycline staining affect the maxillary permanent central incisors?

Correct answer: A. Around 3 years of age

• A. The maxillary permanent central incisors calcify from approximately 3–4 months of age through about 4–5 years. Tetracycline administered around age 3 would incorporate into these teeth during their mineralization window.
• B. Once a tooth erupts, the crown is fully mineralized — tetracycline cannot incorporate into erupted teeth.
• C. Primary teeth can be affected prenatally. The maxillary permanent central incisors form postnatally, not prenatally.
• D. Crown development of the maxillary centrals is largely complete by age 4–5; tetracycline at age 6 would have minimal impact on these teeth.