Pharmacology · single question

Clindamycin is effective against all of the following organisms EXCEPT:

  1. Bacteroides fragilis
  2. Pseudomonas aeruginosa
  3. Staphylococcus aureus (MSSA)
  4. Streptococcus pyogenes
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Correct answer: B. Pseudomonas aeruginosa

  • A. Clindamycin is active against Bacteroides fragilis, making it useful for intraabdominal and anaerobic infections.
  • B. Pseudomonas aeruginosa is a gram-negative aerobic rod intrinsically resistant to clindamycin. Clindamycin works primarily against gram-positive organisms and anaerobes — it has no activity against Pseudomonas. ✓
  • C. Clindamycin covers methicillin-sensitive Staphylococcus aureus (MSSA), and even some MRSA in certain regions.
  • D. Clindamycin covers Streptococcus pyogenes (Group A Strep), one of its classic uses including dental infections.

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