Pharmacology · single question

CASE 8 — What is the mechanism of action of albuterol?

  1. Beta-2 adrenergic agonist
  2. Beta-1 adrenergic agonist
  3. Beta-2 adrenergic antagonist
  4. Beta-1 adrenergic antagonist
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Correct answer: A. Beta-2 adrenergic agonist

  • A. Albuterol (salbutamol) is a SHORT-acting beta-2 adrenergic agonist (SABA). It selectively stimulates β2 receptors in bronchial smooth muscle → bronchodilation. It is the classic rescue inhaler for acute asthma/bronchospasm episodes.
  • B. Beta-1 agonists (e.g., dobutamine) act primarily on the heart — not used for bronchodilation.
  • C. A beta-2 antagonist would cause bronchoconstriction — the opposite and absolutely contraindicated in asthma.
  • D. Beta-1 antagonists (beta-blockers like metoprolol) slow the heart rate.

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