Pharmacology · single question
CASE 5 — What is the mechanism of action of salmeterol?
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Correct answer: C. Long-acting beta-2 adrenergic agonist (LABA)
- A. A beta-2 antagonist would cause bronchoconstriction — the opposite.
- B. Muscarinic agonists cause bronchoconstriction; not therapeutic for asthma.
- C. Salmeterol is a long-acting beta-2 adrenergic agonist (LABA). It selectively stimulates β2 receptors in bronchial smooth muscle → bronchodilation. Used for maintenance therapy in asthma/COPD — NOT as a rescue inhaler.
- D. Alpha-1 antagonists are used for hypertension/BPH; not for asthma.