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Pharmacology · single question

Bupropion is primarily used for which of the following?

  1. Smoking cessation
  2. Opioid addiction treatment
  3. Hypertension management
  4. Anxiety treatment
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Correct answer: A. Smoking cessation

  • A. Bupropion (Zyban) is FDA-approved for SMOKING CESSATION. It is also used for depression (Wellbutrin), but for INBDE purposes, the most tested indication is smoking cessation. Its mechanism involves inhibiting norepinephrine and dopamine reuptake, reducing nicotine cravings.
  • B. Opioid addiction is treated with methadone, buprenorphine, or naltrexone — not bupropion.
  • C. Bupropion is not an antihypertensive — its cardiovascular effects may actually slightly raise blood pressure.
  • D. Bupropion is NOT indicated for anxiety — it can actually worsen anxiety and seizure risk at high doses.

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