An infection from a mandibular molar is MOST likely to spread to which anatomical space?

Correct answer: C. Submandibular space (if apex is below mylohyoid)

• A. Incorrect. The maxillary sinus is involved by MAXILLARY posterior teeth — not mandibular molars.
• B. Incorrect. The lateral pharyngeal space can be secondarily involved but is not the primary space for mandibular molar infections.
• C. Correct. Mandibular MOLAR infections most commonly spread to the SUBMANDIBULAR SPACE when the root apices extend BELOW the attachment of the mylohyoid muscle (which is the case for mandibular second and third molars). The submandibular space is the primary space involved in Ludwig's angina, which originates from mandibular molar infections.
• D. Incorrect. The BUCCAL SPACE is involved when the apex of a mandibular molar is ABOVE the attachment of the buccinator — less common for lower molars.