Among the following DEA schedules, which carries the LOWEST potential for abuse and dependence?

Correct answer: B. Schedule IV

• A. ❌ Schedule I has the HIGHEST abuse potential with no accepted medical use (heroin, LSD, MDMA).
• B. ✅ CORRECT — Abuse potential DECREASES as the schedule number increases. Of the options given, SCHEDULE IV has the lowest potential — this is where benzodiazepines (diazepam, triazolam, alprazolam) and tramadol sit.
• C. ❌ Schedule III sits between II and IV — ketamine, buprenorphine, anabolic steroids, and codeine combinations at lower strengths.
• D. ❌ Schedule II has high abuse potential with accepted medical use — morphine, oxycodone, hydrocodone, fentanyl, amphetamines.

Note: Schedule V is lowest of all (e.g., low-dose codeine cough preparations), but it was not offered here.