Biostatistics & Research · single question

Among randomized controlled trials, cohort studies, and case-control studies, which generally provides the WEAKEST level of evidence due to its retrospective design and susceptibility to recall bias?

  1. Case-control study
  2. Randomized controlled trial
  3. Cohort study
  4. All three provide identical evidence strength
Show answer and explanation

Correct answer: A. Case-control study

Case-control studies, being retrospective and particularly susceptible to recall bias and other forms of bias, are generally considered to provide weaker evidence than cohort studies (which can be prospective) and especially randomized controlled trials (where randomization minimizes confounding and selection bias).

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