Pathology · single question

All of the following are TRUE about Ectodermal Dysplasia EXCEPT:

  1. Anodontia or hypodontia is a common finding
  2. Sparse or absent hair (hypotrichosis)
  3. Inability to sweat properly (anhidrosis)
  4. Adrenal gland dysfunction
Show answer and explanation

Correct answer: D. Adrenal gland dysfunction

Adrenal gland dysfunction is NOT a feature of Ectodermal Dysplasia. The condition affects structures derived from ectoderm: skin (sweat glands, sebaceous glands), hair follicles, nails, and teeth. The adrenal glands are derived from neural crest (medulla) and mesoderm (cortex) — NOT ectoderm. Classic features include hypodontia/anodontia, sparse/brittle hair, anhidrosis, and hypoplastic/absent nails.

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