Pathology · patient case question

What is the appropriate management of this palatal lesion?

Patient case: Palatal changes beneath a maxillary denture in a tobacco user

Patient: Male, 63 years old

Chief Complaint: Routine review of a maxillary complete denture worn for eight years.

Background: Long-standing pipe and cigarette smoker. Wears the denture day and night.

Current Findings: The hard palate is erythematous with a keratotic, leukoplakic background. Numerous small elevated red papules with punctate central openings — inflamed minor salivary gland duct orifices — are visible across the palatal mucosa.

  1. Immediate wide surgical excision of the palatal mucosa
  2. A course of topical nystatin
  3. Relining the denture and reviewing in one year
  4. Tobacco cessation, with reassessment and biopsy of any lesion that persists
Show answer and explanation

Correct answer: D. Tobacco cessation, with reassessment and biopsy of any lesion that persists

  • A. Excision is not indicated for a reversible keratosis. Surgery follows a biopsy diagnosis of dysplasia or malignancy, not the clinical appearance alone.
  • B. Nystatin is an antifungal and treats DENTURE STOMATITIS. Nicotinic stomatitis is a keratotic response to heat, with no fungal component, and will not respond.
  • C. Denture adjustment does not address the aetiology, and a one-year review is too long a delay for a keratotic palatal lesion in a heavy smoker.
  • D. CORRECT. Nicotinic stomatitis in a conventional smoker is REVERSIBLE — the palate typically returns to normal within a few weeks of stopping. Cessation is therefore both the treatment and the diagnostic test. Anything that persists after cessation, or that develops induration or ulceration, must be biopsied.

Note: ⚑ SOURCE CORRECTION — this is worth circulating to the group. The recall keys the treatment of nicotinic stomatitis as NYSTATIN. That is wrong; nystatin belongs to the denture stomatitis item. Two further points make this more than a technicality: in a REVERSE smoker (lit end inside the mouth) nicotinic stomatitis DOES carry real malignant potential and needs biopsy, and beneath a denture the palate is shielded from heat, so keratosis appearing there is more suspicious rather than less.

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