Pharmacology · single question

All of the following are side effects of opioids EXCEPT:

  1. Constipation
  2. Diaphoresis (sweating)
  3. Hyperventilation (increased breathing rate)
  4. Sedation
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Correct answer: C. Hyperventilation (increased breathing rate)

C) Hyperventilation — CORRECT (this is NOT an opioid side effect).
Opioids cause RESPIRATORY DEPRESSION (hypoventilation, decreased respiratory rate) — the opposite of hyperventilation. This is the most dangerous side effect and the cause of opioid overdose deaths.
A) Constipation: Classic opioid side effect due to μ-opioid receptors in the GI tract slowing motility.
B) Diaphoresis (sweating): Common opioid side effect, especially with chronic use or withdrawal.
D) Sedation: Expected CNS depressant effect of opioids.

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