Pharmacology · single question

After a reported penicillin allergy, which symptom would most strongly confirm a TRUE (IgE-mediated) allergic reaction?

  1. Nausea
  2. Vomiting
  3. Urticaria/rash
  4. Diarrhea
Show answer and explanation

Correct answer: C. Urticaria/rash

True IgE-mediated drug allergies present with signs like urticaria, rash, angioedema, bronchospasm, or anaphylaxis. GI symptoms such as nausea, vomiting, and diarrhea are common medication side effects but are not specific markers of a true allergic reaction.

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