Pathology · single question

A white lesion that wipes off with gauze, leaving an erythematous base, is most consistent with which condition — and what is its treatment?

  1. Lichen planus — treated with topical corticosteroids
  2. Leukoplakia — treated with surgical excision
  3. Pseudomembranous candidiasis — treated with an antifungal such as fluconazole or nystatin
  4. Hairy leukoplakia — treated with antivirals
Show answer and explanation

Correct answer: C. Pseudomembranous candidiasis — treated with an antifungal such as fluconazole or nystatin

The 'wipes off' feature is the key distinguishing clue for pseudomembranous candidiasis (thrush) — true leukoplakia and lichen planus do NOT wipe off. Treatment is topical or systemic antifungal therapy (e.g., nystatin suspension/troches or systemic fluconazole).

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