Biostatistics & Research · single question

A study has a 95% Confidence Interval (CI) of (-3.41, 16.41). What is a reasonable conclusion?

  1. Results are NOT statistically significant; null hypothesis cannot be rejected
  2. Results are statistically significant; null hypothesis can be rejected
  3. Results are significant because the range includes 0
  4. Results are not significant only because the lower CI is negative
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Correct answer: A. Results are NOT statistically significant; null hypothesis cannot be rejected

A 95% CI of (-3.41, 16.41) INCLUDES ZERO. If the CI includes zero, there is NO statistically significant difference — we cannot reject the null hypothesis. Statistical significance requires the CI to EXCLUDE zero. Since 0 falls within this interval, the data are consistent with no effect.
  • A. Incorrect. Results are NOT significant because the CI includes zero.
  • B. Incorrect. The results are NOT significant BECAUSE the range includes 0 — this is a wrong conclusion.
  • C. CORRECT. CI of (-3.41, 16.41) includes 0 → results are not statistically significant → null hypothesis cannot be rejected.
  • D. Incorrect. The reason for non-significance is the CI INCLUDING ZERO — not merely that the lower bound is negative.

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