Anesthesia · single question

A study comparing the efficacy of articaine and lidocaine reports a relative risk (RR) of 3.1 with a 95% confidence interval (CI) of 2.1–4.7 and a p-value <0.001. Based on this data, what can be concluded about the efficacy of these anesthetics?

  1. Articaine is safer to use than lidocaine
  2. Lidocaine is more effective than articaine
  3. Articaine is more effective than lidocaine
  4. Articaine and lidocaine have the same efficacy
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Correct answer: C. Articaine is more effective than lidocaine

The study shows a relative risk (RR) of 3.1, meaning patients receiving articaine were approximately 3 times more likely to achieve successful anesthesia compared to lidocaine. The 95% confidence interval (CI) of 2.1–4.7 contains the point estimate of 3.1 and does not cross 1.0, confirming the result is statistically significant. The p-value <0.001 further supports this finding, indicating a very low probability that the observed effect is due to chance. Therefore, the study strongly suggests that articaine is more effective than lidocaine.

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