Pathology · single question

A smoker has a whitish lesion on the tongue that has NOT resolved. What is the FIRST step?

  1. Refer to oncology
  2. Incisional biopsy immediately
  3. Prescribe antifungal medication
  4. Advise the patient to quit smoking and re-evaluate
Show answer and explanation

Correct answer: D. Advise the patient to quit smoking and re-evaluate

  • A. Incorrect. Oncology referral is premature before attempting conservative management and biopsy.
  • B. Incorrect. Biopsy is indicated if the lesion persists after eliminating the irritant (tobacco) — not as the immediate first step before trying to remove the cause.
  • C. Incorrect. Antifungal therapy is appropriate if the lesion is wiped off (candidiasis). A persistent white lesion that is NOT wiped off requires different management.
  • D. Correct. For a SMOKER with a persistent white lesion on the tongue, the FIRST step is to ADVISE THE PATIENT TO QUIT SMOKING and schedule a re-evaluation in 2–3 weeks. Some tobacco-related white lesions (smoker's keratosis) will RESOLVE with smoking cessation — allowing differentiation from true leukoplakia. If the lesion PERSISTS after cessation, BIOPSY is the next step.

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