Pathology · single question

A 23-year-old male has a white edematous lesion on the left buccal mucosa that disappears when the mucosa is stretched. What is the diagnosis?

  1. White sponge nevus
  2. Lichen planus
  3. Squamous cell carcinoma
  4. Leukoedema
Show answer and explanation

Correct answer: C. Squamous cell carcinoma

  • A. Incorrect. Lichen planus striae persist when stretched and do not disappear.
  • B. Incorrect. SCC is indurated, irregular, and never disappears with stretching.
  • C. Correct. Leukoedema is a benign variation of normal appearing as filmy, gray-white opalescence on buccal mucosa that disappears or lessens when stretched. It is more common in African Americans and is a normal anatomic variant.
  • D. Incorrect. White sponge nevus is hereditary and does not disappear with stretching.

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