Medical Emergencies · single question

A patient's hepatitis B serology shows isolated POSITIVE anti-HBs with NEGATIVE HBsAg and NEGATIVE anti-HBc. This pattern indicates the patient is:

  1. Acutely infected
  2. Chronically infected
  3. Vaccinated / immune
  4. Never exposed and non-immune
Show answer and explanation

Correct answer: C. Vaccinated / immune

  • A. Acute infection shows HBsAg+ and IgM anti-HBc+.
  • B. Chronic infection shows persistent HBsAg+.
  • C. Correct. Isolated anti-HBs (without anti-HBc) indicates vaccine-acquired immunity.
  • D. Never-exposed patients are negative for ALL markers, including anti-HBs.

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