A patient with testicular cancer on multiple medications and other conditions requires an antibiotic for a dental infection. Which antibiotic would be most appropriate?

Correct answer: A. Ciprofloxacin

• A. CORRECT. Ciprofloxacin is a broad-spectrum fluoroquinolone with activity against a wide range of gram-negative and gram-positive bacteria. In cancer patients with multiple comorbidities and medications, ciprofloxacin may be selected for its broad coverage and suitability when standard antibiotics are contraindicated or have drug interactions.
• B. Penicillin VK has a narrow spectrum and may be insufficient for complex infections in immunocompromised patients such as those undergoing cancer treatment.
• C. Azithromycin has significant drug-drug interaction potential (QT prolongation) and may interact with medications used in cancer patients. It is not the preferred choice here.
• D. Tetracyclines are contraindicated in patients under 8 years and can interact with several medications. They are not the preferred choice for a patient with multiple complex medical conditions and cancer history.