Physiology & Biochemistry · single question

A patient with cancer, hyperparathyroidism, and hyperkalemia — what is the most likely cause of the hyperkalemia?

  1. The underlying malignancy
  2. Vitamin D deficiency
  3. Hyperparathyroidism itself
Show answer and explanation

Correct answer: A. The underlying malignancy

Hyperparathyroidism's primary metabolic effect is on calcium and phosphate (causing hypercalcemia), not potassium — it is not a direct, expected cause of hyperkalemia. The underlying malignancy (through mechanisms like tumor lysis, paraneoplastic effects, or renal involvement) is the most plausible explanation for hyperkalemia among the choices given.

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