Pharmacology · single question

A patient taking apixaban requires oral surgery with significant bleeding risk. Standard guidance is to:

  1. Continue without interruption always
  2. Stop it approximately 2 days before surgery (per physician)
  3. Stop it for 14 days
  4. Reverse it routinely with vitamin K
Show answer and explanation

Correct answer: B. Stop it approximately 2 days before surgery (per physician)

  • A. For higher-bleeding-risk surgery, brief interruption may be advised in consultation with the physician.
  • B. Correct. For procedures with meaningful bleeding risk, apixaban is commonly held ~48 hours (2 days) beforehand, coordinated with the prescriber.
  • C. A 14-day hold is excessive and raises thrombotic risk.
  • D. Vitamin K reverses warfarin, not the direct factor Xa inhibitor apixaban.

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