Pathology · single question

A patient presents with a single, asymptomatic soft-tissue nodule on the buccal mucosa with a smooth surface and normal pink color, consistent with chronic trauma from cheek biting. What is the most likely diagnosis?

  1. Papilloma
  2. Traumatic fibroma
  3. Pyogenic granuloma
  4. Monomorphic adenoma
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Correct answer: B. Traumatic fibroma

The traumatic fibroma (also called irritation fibroma) is the most common soft-tissue tumor-like lesion in the oral cavity. It is a reactive hyperplasia of fibrous connective tissue in response to chronic local irritation (cheek biting, denture flanges, or other trauma). It presents as a smooth-surfaced, firm, pink-colored nodule, most commonly on the buccal mucosa along the occlusal line. It is asymptomatic and does not recur after simple excision. Papilloma is typically exophytic with a cauliflower surface texture. Pyogenic granuloma is highly vascular and bleeds easily. Monomorphic adenoma is a salivary gland tumor.

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