Pathology · single question
A patient presents with a purple-colored oral lesion. Clinical examination reveals no amalgam restorations on surrounding teeth and no visible foreign body. What is the most likely diagnosis?
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Correct answer: A. Vascular lesion (hemangioma or varix)
A purple oral lesion in the absence of amalgam or other foreign body is most consistent with a vascular lesion, such as a hemangioma or oral varix. Hemangiomas appear as bluish-purple, soft, compressible lesions that blanch on diascopy (pressure with a glass slide). An oral varix is a dilated vein, commonly seen on the ventral tongue or buccal mucosa in older patients. Amalgam tattoos are gray-blue-black macules directly associated with amalgam restoration or instrument contamination. Melanotic macules are brown to dark brown. While Kaposi sarcoma also presents as a purple lesion, it is associated with immunosuppression (HIV) and its distribution is more specific. The absence of amalgam makes amalgam tattoo unlikely.