Pathology · single question

A patient presents with a bump on the tongue. Which lesion is LEAST likely in the differential?

  1. Granular cell tumor
  2. Lingual thyroid
  3. Pleomorphic adenoma
  4. Fibroma / traumatic fibroma
Show answer and explanation

Correct answer: C. Pleomorphic adenoma

  • A. Granular cell tumor has a marked predilection for the dorsal tongue.
  • B. Lingual thyroid presents as a posterior midline dorsal tongue mass at the foramen cecum.
  • C. Correct. Pleomorphic adenoma arises in major salivary glands (85% parotid) and minor glands of the palate/upper lip. The tongue has very few minor salivary glands, making this location distinctly uncommon.
  • D. Traumatic fibroma is one of the most common tongue masses, from chronic biting.

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