Pharmacology · single question

A patient on apixaban had an extraction and calls several hours later reporting continued oozing despite biting on gauze. What is the BEST response?

  1. Ask her to come to the office so you can evaluate and achieve local hemostasis
  2. Tell her to double the gauze and that nothing further is needed
  3. Instruct her to stop taking apixaban until the bleeding stops
  4. Tell her to wait until her next dose of apixaban is due
Show answer and explanation

Correct answer: A. Ask her to come to the office so you can evaluate and achieve local hemostasis

  • A. CORRECT. Post-extraction bleeding in an anticoagulated patient is managed with LOCAL measures — but it must be EVALUATED. Bring the patient in, remove the clot, identify the source, and apply local hemostatics: oxidized cellulose or gelatin sponge in the socket, sutures, firm pressure, and tranexamic acid mouthwash (4.8%, held 2 minutes, four times daily for 2–5 days). This is highly effective and avoids any change to anticoagulation.
  • B. Dismissing continued bleeding without assessment risks a large hematoma, airway compromise in the floor of the mouth, or significant blood loss.
  • C. NEVER instruct a patient to alter anticoagulation on their own — the thromboembolic risk (stroke, PE) far exceeds the bleeding risk from a dental socket, and only the prescribing physician should make that decision.
  • D. Waiting for the next dose does nothing to control active bleeding and delays care.

Note: Local hemostasis works. Tranexamic acid rinse is the single most useful adjunct and is under-used.

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