Pharmacology · single question
A patient is taking isoniazid (for tuberculosis treatment or prophylaxis). What is a major, classically tested side effect of this medication?
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Correct answer: A. Hepatitis (hepatotoxicity) — a major, well-documented isoniazid side effect requiring liver function monitoring
Isoniazid carries a significant risk of hepatotoxicity (drug-induced hepatitis), requiring baseline and periodic liver function monitoring during therapy. It can also cause peripheral neuropathy (related to vitamin B6/pyridoxine depletion, often co-prescribed to mitigate this risk), but hepatotoxicity is the most emphasized, potentially serious side effect.