Pathology · single question

A patient has small red vesicular lesions on the hard palate next to an amalgam on #14, appearing during stress. Biopsy is performed. What is most likely seen histologically?

  1. Koilocytes
  2. Tzanck cells
  3. Civatte bodies
Show answer and explanation

Correct answer: B. Tzanck cells

  • A. INCORRECT. Koilocytes indicate HPV infection.
  • B. CORRECT. Recurrent intraoral herpes on keratinized mucosa (hard palate) shows Tzanck cells, the multinucleated giant cells with viral cytopathic change.
  • C. INCORRECT. Civatte bodies (colloid bodies) are seen in lichen planus, not herpetic lesions.

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