Pathology · single question

A patient has recurrent herpes labialis. The virus stays latent in the trigeminal ganglion. When reactivated, it travels to the oral mucosa through:

  1. Blood vessels
  2. Lymphatic vessels
  3. Axons of sensory neurons
  4. Saliva
Show answer and explanation

Correct answer: C. Axons of sensory neurons

  • A. HSV does not travel via the bloodstream during reactivation.
  • B. HSV does not travel via lymphatics during reactivation.
  • C. Correct. HSV travels along the axons of sensory neurons from the trigeminal ganglion to the site of reactivation in the oral mucosa/perioral skin.
  • D. Saliva is not the transport mechanism for viral reactivation within the host (though it can be a vehicle for transmission to others).

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