Pathology · single question
All of the following are features of Ectodermal Dysplasia EXCEPT:
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Correct answer: D. Y-linked inheritance
Ectodermal dysplasia is X-linked recessive (most common form), NOT Y-linked. Because the EDA gene is on the X chromosome, hemizygous males (XY) are fully affected while heterozygous females (XX) may be carriers with mild or no symptoms. Y-linked inheritance would mean only fathers pass it to all sons — that is not the pattern here. Dry skin (anhidrosis), brittle/sparse hair, and male predominance are all correct features.