Pathology · single question

All of the following are features of Ectodermal Dysplasia EXCEPT:

  1. Dry skin (anhidrosis)
  2. Brittle hair (hypotrichosis)
  3. More common in males than females
  4. Y-linked inheritance
Show answer and explanation

Correct answer: D. Y-linked inheritance

Ectodermal dysplasia is X-linked recessive (most common form), NOT Y-linked. Because the EDA gene is on the X chromosome, hemizygous males (XY) are fully affected while heterozygous females (XX) may be carriers with mild or no symptoms. Y-linked inheritance would mean only fathers pass it to all sons — that is not the pattern here. Dry skin (anhidrosis), brittle/sparse hair, and male predominance are all correct features.

Practice Pathology questions Pathology study notes

More Pathology practice questions