Pathology · single question

A patient has aphthous ulcers on the buccal mucosa. What is the most likely cause?

  1. Unknown etiology
  2. Fungi
  3. Bacteria
  4. Virus
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Correct answer: A. Unknown etiology

  • A. Recurrent aphthous stomatitis (RAS) has an UNKNOWN exact etiology. Contributing factors include immune dysregulation, trauma, stress, nutritional deficiencies, and genetic predisposition, but no single causative agent has been identified.
  • B. Fungi do not cause aphthous ulcers.
  • C. Bacteria do not cause aphthous ulcers directly.
  • D. Aphthous ulcers are NOT caused by viruses (unlike herpetic ulcers, which are viral and have different clinical features).

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