Pathology · single question

A patient has a white lesion that CAN be wiped off. Which diagnosis should be excluded from the differential?

  1. Leukoplakia
  2. Chemical burn slough
  3. Pseudomembranous candidiasis
  4. Materia alba / food debris
Show answer and explanation

Correct answer: A. Leukoplakia

  • A. Correct. Leukoplakia is by definition a white plaque that CANNOT be scraped off and cannot be attributed to any other condition. Wipeability immediately excludes it.
  • B. A chemical burn produces a sloughing necrotic membrane that wipes away.
  • C. Pseudomembranous candidiasis is the classic wipeable white lesion, leaving an erythematous base.
  • D. Materia alba and debris wipe off readily.

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