Pathology · single question

A patient presents with a swelling in the submandibular area that specifically worsens during meals. What is the most likely diagnosis?

  1. Lymphadenopathy
  2. Cellulitis
  3. Submandibular salivary gland obstruction (sialolithiasis)
  4. Salivary gland neoplasm
Show answer and explanation

Correct answer: C. Submandibular salivary gland obstruction (sialolithiasis)

  • A. Incorrect. Lymphadenopathy does not characteristically swell during mealtimes.
  • B. Incorrect. Cellulitis presents with diffuse erythema, warmth, and fever — and does NOT specifically worsen with meals.
  • C. CORRECT. Swelling that worsens specifically during meals is pathognomonic for salivary gland obstruction (sialolithiasis). Eating stimulates salivary secretion; when the duct is blocked (usually by a calculus in Wharton's duct), the gland cannot drain and swells painfully. Symptoms subside between meals as salivary stimulation decreases.
  • D. Incorrect. Salivary gland neoplasms typically present as painless, slow-growing masses not correlated with meals.

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