Oral Surgery · single question

A patient falls from left lateral excursion causing 5+ mm passive stretch pain. The best initial medication for this TMJ myofascial pain is:

  1. Cyclobenzaprine (muscle relaxant — first-line pharmacotherapy for myofascial pain)
  2. Diazepam
  3. Codeine
  4. Ibuprofen alone
Show answer and explanation

Correct answer: A. Cyclobenzaprine (muscle relaxant — first-line pharmacotherapy for myofascial pain)

  • A. Correct. For TMJ MYOFASCIAL PAIN (muscle pain), cyclobenzaprine (a central-acting muscle relaxant) is a commonly used pharmacological adjunct alongside splint therapy and physical therapy. It reduces muscle spasm and hyperactivity. Combined with NSAIDs (ibuprofen), it provides effective short-term pain control.
  • B. Diazepam has muscle relaxant properties but carries higher addiction potential and CNS depression compared to cyclobenzaprine for this indication.
  • C. Codeine (opioid) is not appropriate first-line for myofascial TMJ pain — addiction risk without superior efficacy.
  • D. Ibuprofen alone addresses inflammation but does not address the muscle spasm component as effectively as the combination with a muscle relaxant.

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