Pathology · single question
A child with Ectodermal Dysplasia (no teeth, peri-orbital wrinkles, dry skin) also has which additional associated feature?
Show answer and explanation
Correct answer: B. Palmo-plantar hyperkeratosis
- A. ❌ Bifid ribs are associated with Gorlin-Goltz (nevoid basal cell carcinoma) syndrome.
- B. ✅ Correct per source. Palmo-plantar hyperkeratosis (thickened skin of palms and soles) is associated with some ectodermal dysplasia variants, particularly those overlapping with Papillon-Lefèvre syndrome.
- C. ❌ Dry eyes are associated with Sjogren's syndrome, not primarily ectodermal dysplasia.
- D. ❌ Craniosynostosis is associated with Apert and Crouzon syndromes.