Pharmacology · single question
A child on buspirone develops persistent involuntary, repetitive purposeless movements after stopping the medication. What is this adverse effect?
Show answer and explanation
Correct answer: A. Tardive dyskinesia
Tardive dyskinesia (tardive = delayed) = late-onset involuntary repetitive purposeless movements from dopamine-blocking agents (antipsychotics, metoclopramide, buspirone). Classic orofacial movements: lip smacking, tongue protrusion, grimacing. Often irreversible. Source confirms: 'Side effect buspiron = tardive dyskinesia.'
- A. CORRECT. Tardive dyskinesia = late-onset, persistent involuntary movements. Side effect of buspirone and dopamine-blocking agents.
- B. Neuroleptic malignant syndrome = life-threatening hyperthermia + rigidity + autonomic instability — not repetitive movements.
- C. Acute dystonia = early-onset (hours) sustained muscle spasm from dopamine antagonists — reversible with anticholinergics.
- D. Akathisia = inner restlessness/inability to sit still — not involuntary repetitive movements.