Pediatric Dentistry · single question

A child bit his cheek after his last appointment. The mother wants medication to reverse the anesthetic effect. What can you give?

  1. Phentolamine mesylate (OraVerse)
  2. Phenoxybenzamine
  3. Atropine
  4. Epinephrine
Show answer and explanation

Correct answer: A. Phentolamine mesylate (OraVerse)

PHENTOLAMINE MESYLATE (OraVerse) is the only FDA-approved LOCAL ANESTHETIC REVERSAL AGENT for dental use. It is an alpha-adrenergic blocker that COUNTERACTS the vasoconstriction caused by epinephrine in the LA, allowing increased blood flow and faster clearance of the local anesthetic from the site. It is particularly useful in pediatric patients to prevent self-injury from biting numb lips/cheeks. Phenoxybenzamine (B) is also an alpha blocker but not the dental-specific agent. A is correct.

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