Pathology · single question

A 65-year-old woman (breast cancer 2 years ago) has bone loss in all upper-left quadrants and a multilocular, soap-bubble radiolucent lesion between #2 and #3. Most likely diagnosis?

  1. Traumatic bone cyst
  2. Bone metastasis
  3. Ameloblastoma
  4. Odontogenic keratocyst (OKC)
Show answer and explanation

Correct answer: C. Ameloblastoma

  • A. Incorrect – usually a unilocular radiolucency scalloping between roots, not multilocular soap-bubble.
  • B. Incorrect – the breast-cancer history is a distractor; metastases are usually ill-defined/ragged, not soap-bubble multilocular.
  • C. Correct – a multilocular 'soap-bubble' radiolucency is the classic radiographic hallmark of ameloblastoma.
  • D. Incorrect – OKCs are typically well-defined and grow antero-posteriorly without expanding; not classic soap-bubble.

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