Pathology · single question

A 28-year-old female patient (not pregnant) presents with a painless, vascular, pedunculated red lesion on the gingiva that bleeds easily. What is the MOST likely diagnosis?

  1. Peripheral giant cell granuloma
  2. Pyogenic granuloma (lobular capillary hemangioma)
  3. Kaposi sarcoma
  4. Peripheral ossifying fibroma
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Correct answer: B. Pyogenic granuloma (lobular capillary hemangioma)

A Pyogenic granuloma (lobular capillary hemangioma) is a benign, vascular, red, pedunculated soft tissue growth that bleeds easily. It is NOT caused by pyogenic bacteria — the name is a misnomer. It is a reactive hyperplastic response to minor trauma, hormonal changes (pregnancy granuloma), or local irritation. It appears on the gingiva most commonly. In a non-pregnant woman, it is still common from local irritants. Treatment is surgical excision with elimination of the cause.

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