Pathology · single question

A radiolucent lesion is found between the roots of teeth #13 and #14 on a radiograph, appearing cyst-like. Which of the following CANNOT be included in the differential diagnosis?

  1. Odontogenic keratocyst (OKC)
  2. Lateral periodontal cyst
  3. Ameloblastoma
  4. Traumatic bone cyst
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Correct answer: C. Ameloblastoma

A radiolucent lesion located laterally between the roots of teeth #13 (maxillary left canine) and #14 (maxillary left first premolar) in a unilocular cyst-like appearance is most consistent with a lateral periodontal cyst or an OKC. Traumatic bone cysts can occur in this region (though more common in the mandible). Ameloblastoma is almost exclusively a mandibular lesion (80% in the posterior mandible) and is typically multilocular; it would be the LEAST likely diagnosis in the maxillary premolar region. Therefore, ameloblastoma cannot be included in the differential diagnosis for this location.

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