Micro & Immunology · single question
A 10-year-old develops diarrhea, nausea, vomiting, and a rash shortly after receiving local anesthesia. The reaction is best classified as:
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Correct answer: A. Type I (immediate, IgE-mediated) hypersensitivity
- A. Correct. A rapid reaction with urticaria/rash and GI symptoms after exposure is an immediate IgE-mediated (type I) hypersensitivity.
- B. Type II is antibody-mediated cytotoxicity (e.g., hemolytic reactions).
- C. Type III is immune-complex disease (e.g., serum sickness, days later).
- D. Type IV is delayed/T-cell mediated, appearing 24–72+ hours later.
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