Micro & Immunology · single question
A patient presents with an acute illness. Which immunoglobulin is ELEVATED FIRST?
Show answer and explanation
Correct answer: B. IgM
IgM is the first immunoglobulin produced in response to a new antigen — it characterizes the acute/primary immune response.
- A. ❌ IgA is the secretory immunoglobulin in mucosal secretions; not the first systemic response.
- B. ✅ CORRECT – IgM is the first antibody produced; elevated IgM indicates recent/current acute infection.
- C. ❌ IgE mediates type I hypersensitivity; not the primary acute infection antibody.
- D. ❌ IgG is produced later; dominant in the secondary response.
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