Pathology · single question
With a vitamin C (ascorbic acid) cofactor deficiency, which enzyme fails to function, impairing collagen formation?
Show answer and explanation
Correct answer: D. Lysyl hydroxylase
- A. Incorrect – lysyl oxidase requires COPPER, not vitamin C.
- B. Incorrect – not vitamin C–dependent for collagen synthesis.
- C. Incorrect – not the vitamin C–dependent collagen enzyme.
- D. Correct – vitamin C is the cofactor for prolyl/LYSYL hydroxylase; without it, collagen cross-linking fails (scurvy: bleeding gums, poor healing).