Pathology · single question
Which test is NOT a specific diagnostic test for Sjögren's syndrome?
Show answer and explanation
Correct answer: A. CBC (Complete Blood Count)
- A. Correct (the exception). CBC is a general, nonspecific lab test and is not part of the specific diagnostic criteria for Sjögren's syndrome.
- B. Minor salivary gland (lip) biopsy is the gold standard diagnostic test for Sjögren's syndrome, showing focal lymphocytic sialadenitis.
- C. Anti-SSA/Ro and anti-SSB/La autoantibodies are core serologic diagnostic markers for Sjögren's syndrome.
- D. The Schirmer test measures tear production and is a standard component of the Sjögren's diagnostic workup (assessing dry eyes).
Note: One exam question presented a list of Sjögren tests in an 'EXCEPT' format; CBC was the exception (not a specific Sjögren's test).