Restorative & Materials · single question

Which substance does NOT DIRECTLY affect REMINERALIZATION of enamel?

  1. Fluoride (directly promotes fluorapatite formation)
  2. Salivary calcium and phosphate ions (directly remineralize)
  3. Salivary pH buffering capacity (directly neutralizes acid)
  4. Salivary immunoglobulin (IgA) — does NOT directly remineralize
  5. Casein phosphopeptide (CPP-ACP)
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Correct answer: D. Salivary immunoglobulin (IgA) — does NOT directly remineralize

✓ D) Salivary IgA does NOT directly affect remineralization.
Remineralization factors: Fluoride (converts hydroxyapatite to fluorapatite), salivary Ca²⁺ and PO₄³⁻ ions (directly deposit on demineralized enamel), salivary proteins (statherin, proline-rich proteins — stabilize calcium), saliva pH/buffering (neutralizes acid to allow remineralization), CPP-ACP (Recaldent), GC MI Paste. Salivary IgA: antibacterial (agglutinates bacteria for swallowing/clearance) but does NOT directly provide minerals to enamel. It has an INDIRECT role (reduces bacteria) but not a direct remineralization role. This distinction is tested.

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