Public Health · single question

Which property of fluoride is MOST relevant to its cariostatic effectiveness?

  1. Concentration in community water
  2. Solubility in acidic conditions
  3. Substantivity (prolonged retention at tooth surface)
  4. Fluoride bioavailability in salivary flow
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Correct answer: C. Substantivity (prolonged retention at tooth surface)

SUBSTANTIVITY = fluoride's ability to bind to tooth surfaces and be slowly released over time. High substantivity ensures prolonged protective effect. Why fluoride varnish is effective despite periodic application — it binds tightly to enamel and releases fluoride slowly.

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