Periodontics · single question
Which phase of wound healing is responsible for maintaining the initial coagulum and achieving hemostasis immediately after tissue injury?
Show answer and explanation
Correct answer: A. Inflammatory phase
The inflammatory phase is the first phase of wound healing, beginning immediately after tissue injury (within seconds to minutes). It achieves hemostasis through: vasoconstriction, platelet aggregation and activation, formation of the fibrin clot (coagulum), followed by vasodilation and increased vascular permeability allowing immune cell infiltration. The coagulum serves as a scaffold for subsequent healing. Neutrophils arrive first (within hours), followed by macrophages (48-72 hours), which orchestrate the transition to proliferative healing. In dental extraction sockets, maintaining the blood clot is critical — its premature loss causes dry socket (alveolar osteitis). The proliferative phase involves granulation tissue formation, angiogenesis, and wound contraction.